What are 5 amino acids whose side chain can hydrogen bond with water?
What are 5 amino acids whose side chain can hydrogen bond with water? Why?
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Answer by jbower205
There are quite a few possibilities, but the most obvious are Aspartate, asparagine, glutamate, serine, threonine, glycine - possibly cysteine, tyrosine, and glutamine as well. All of the afformentioned AAs contain side chains that have available lone pairs to accept hydrogen bonds from water (H-bond acceptors) or have available hydrogen atoms to donate to water (H-bond donors). For example, Asparagine and Glutamine have Nitrogen atoms in their side chains which are electron withdrawing - this makes the H-atoms bonded to the N-atom more available for H-bonding. The N-atom also has a lone pair of electrons which can accept a H-atom from water. The same goes for the AAs with Hydroxyl side chains (i.e. serine, threonine, tyrosine).
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